Some bacteria, such as the Klebsiella pneumoniae
bacteria shown in these 1000 X images, produce capsules. Capsules
are made of sticky substances such as polysaccharides that are secreted by the bacteria and adhere to the
cell. Capsules inhibit phagocytosis in the infected host and thus enhance
survival of the bacteria. Anthony's method, a negative staining technique,
was used to make the capsules visible in these images. Utilizing crystal
violet and copper sulfate, Anthony's method results in a dark purple background
and purple rod-shaped Klebsiella bacteria surrounded
by white (refractile) capsules.
Click on each image to see the enlarged version.
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