(Alternate spelling, 'scepticism') In Epistemology, the view that we cannot have knowledge.

Skepticism may apply to many areas of knowledge; one might be skeptical of the ability to have accurate knowledge of morality (Moral Skepticism), or more generally, of the world around us. There are strong and weak versions of skepticism which claim that we cannot have any knowledge at all, or that we cannot have any significant knowledge of the world, respectively.

For example, one might think we are epistemically limited in regard to any beliefs dependent on sensation while at the same time admitting we can have accurate knowledge of matters of reason (i.e., things which are true by definition, or mathematics, etc.). Alternatively, one might be skeptical of the possibility of having any knowledge whatsoever (radical or extreme skepticism).